I have only one season's experience over six hives using Apivar, which is notably, a synthetic compound which has some drawbacks which do not appear to attach to oxalic treatments. But I have found that by using it exactly according to instructions it has been extremely effective in controlling varroa. I didn't need to monitor varroa drop because the correct use should cause most of them to drop in any case....no follow up needed.
It's seems possible that tolerance may develop over years, but using one application per year and removing the strips at the right time, I hope to avoid this.
I'm not persuaded that using oxalic crystals is as straightforward as I would like my beekeeping to be, but I can see that it is the "direction of travel" for beekeeping judged by comments here.