I thought it would help to put some things into perspective here.
I live in Ormidheia Village in eastern Cyprus. The village is located in a shallow valley near the coast. We have 4 beekeepers in the village parish with about 700 hives in total, most colonies have our genetics. The surrounding area is mostly arable land with winter wheat and potatoes. It is likely that virgin queens raised in the area will mate with drones from these hives. In addition, there are many hives in surrounding villages that also carry our genetics.
Whilst not actively selecting for VSH, we see that many of our colonies uncap and recap brood, Varroa levels are now the lowest we have seen for 35 years. Usually, we would expect to see some bees with viral damage, but not so this year.
The photographs in the original post are of a nuc that was part of a cell starter hive in October. This hive had continual boost input of sealed brood and was split into nucs when it started showing signs of laying workers. The nuc was given a sealed queen cell and the queen was open-mated. The addition of the sealed brood, of course, means that the Varroa population was also boosted and we can see that the bees have reacted to this by uncapping.
We also observe that a high level of uncapping is detrimental and the colony can die because it just runs out of bees, especially in late summer when dearth causes a reduction in brood production. This was confirmed in a discussion with some of our colleagues in Germany. A low to medium uncapping is desirable. VSH is not the end of the story with Varroa, but an extremely useful behaviour to have in our bees.
In VSH projects where single drone inseminations were used, the colonies have a below-average production obviously because of low diversity and vigour, but they are working on this and will rectify it.
The target is to have treatment-free bees before 2030, can it be accomplished? Yes, I think it can.