Nucs for summer use or for over-wintering? Think ahead for your possible future requirements.
What format? Historically, the eleven frame National led naturally, or conveniently to the half sized footprint for the five framed nuc - two could sit under a National roof if you wanted.
6 frames is so much easier for overwintering - and consider making some shallow boxes for feeding, maybe.
Very deep roofs may be a good plan if over-wintering - can cover a shallow box plus insulation on the top and still come down over the main box.
My nuc floors were separate, but the most are now screwed on. I use some odd floorless ones if uniting to change queens.
All my floors are ventilated (no top ventilation at all) for over-wintering. I may not have gone that way so positively if my nucs were just on deep frames. The bulk of mine are 6 frame polys and they don't really need any extra stores to go through the winter quite easily. Almost as big as a deep box, after all!
All entrances are bottom slots for the same reason as derekm, plus it is easier for the bees to clear out any corpses. If using solid floors and elevated entries, give consideration to drainage. OMFs can be partly or completely sealed in very cold weather if required, but remember that the bees cannot clear away the detritus trapped between floor and solid board.
Top insulation is required if overwintering (a couple of mine have had two x 18mm coverboards before now), end panels can be filled with insulation, if they are constructed on similar lines to the National boxes. That leaves the sides to be dealt with.
Now if only for summer use....... much less to think about. If used as bait hives (doubled up?) The top will need a detachable floor and the bottom a solid floor.
So lots to think about, depending on format and use. Have fun.