A wipe with a rag (with a few drops of clove oil) is better than smoke at covering up sting pheromones - so one sting doesn't become several.
I have one extremely nervous colony. For example, any frame bumping sets them off much more than not just my others, but I think any others that I've met.
Point is, that with them, I've taken to washing gloves and hive tool after every couple of frames, to keep them disinterested.
Clove oil wiping of clean gloves before starting that hive was not enough to get them to leave my fingers alone.
Incidentally, this queen was fine previously and the 'nervousness' has only appeared after an A/S and combination with a Q- (single QC failed) rump from another A/S. Hope their high strung nature doesn't lead to Q being balled. (Saw her at the weekend, so she is coping.) I'm going to live with it for another month before making any "life-changing" decisions.