I smoke, just a wisp or 2 across the entrance, normally smoke the hive ahead whilst working on current one. Always at hand for keeping a level of control if required.
Working yesterday on my biggest hive, 10 frames of brood in a 14x12 with 5 supers and you have no choice, each super splits away from the previous leaving exposed runny honey that the bees lap up and wont shift without a puff or 2, its either that or crush them during reassembly. Lifting 2 at a time wasnt possible due to the weight.
This hive has given 140lb already with another 50+ to come this weekend.
To a relative beginner like me a big / strong / full hive can be a bit daunting when compared to the normal 8 - 9 frames in a std brood with a super or 2, so I like to have the smoker as a back up to my confidence.
Last year a normal peaceful hive turned halfway through an inspection and I got 20 odd stings whilst closing up, without a smoker I would of been a lot longer and clumsier.