Isn't the 'efficiency' of a hive always disrupted when we open a hive either with or without the use of smoke? Once we start moving frames around we have already upset their environment. At least new keepers are taught (I think) to place frames carefully back in the same order.What is interesting me is what effect on the efficiency of the colony/super-organism, whenever bees of different ages/gland development are induced away from the area in the nest where they were carrying out the tasks appropriate to their age, and induced to fill up with honey, because of smoke/opening the hive triggering an old instinct to prepare for repairing damage to their nest caused by fire or attack by a predator (today, by a beekeeper).
posters on this thread seem unconcerned by this - or simply not thinking about it.
I suspect that most do not think about the effect smoke may have on the efficiency of a colony, I think for most its more a matter of control and subjugating bees and nature.