Buzz, the direct answer to your question is that because all enzymes are proteins that they are vulnerable to thermal degradation. Enzymes are a pain in many food manufacture processes, heat is often the method used to knock them out where other changes like pH can't be used to supress activity.
Depending on their structure, the level of free moisture (which is low in honey - circa <18%). Most can be knocked back to less than 5% of their original activity by 75'C for 5 minutes in low moisture environments you have to go higher 85'C/5 mins, some need 90/10 etc etc. Your list of invertase, diastase, glucose oxidase and catalase in honey should all cop it by 80'C.
But as previously asked on this thread, why bother to knock out what the bees put in there in the first place? they are 'health' inert proteins and by definition already present in the bees digestive tract.
As an aside heating will also cause carbohydrate degradation and the formation of hydroxymethylfurfural (HMF) but whilst detrimental to the eating and keeping qualities of honey I cant see it being a problem with regard a bee feeding regime.
Still not sure why you’d want to though? Please explain.