In the long term there is a possibility if used over many generations of breeding.
Theoretically but unlikely in the case of fipronil custard because of the highly targetted method of application. 'Biological' resistance is a function of population numbers and exposure, i.e. there has to be a viable cohort of survivors to breed to pass on 'immunity'. With velutina, the sexuals represent a miniscule fraction of the population so it would be very difficult for velutina to develop resistance within a meaningful period of time.
I don't doubt that it's theoretically possible all things being equal but the likelihood is very small with fipronil custard. In the tick example you cite there is a long term low level diminishing exposure to fipronil. So even when administered orally or by injection fipronil will persist for up to 21 days. Not only is there therefore constant exposure at high tick population levels to favour survivor reproduction, as the fipronil residues taper off they become sub lethal which further aids development of resistance in otherwise more susceptible individuals. Notwithstanding all of this, resistance in ticks is still relatively low.
If I'm understanding things correctly the death of the queen [is?] fairly rapid, thus the colony will fail and with good timing no Queens should emerge that can be mated to produce young with resistant traits.
Indeed but there is also another feature of the fipronil custard method which significantly reduces risk of resistance further. The method allows for a higher target dose of fipronil to be administered which reduces the chance of survival considerably as resistance is also linked to dose.
And to the compost pile?
vegan option
Vegans do not consume protein of animal origin, so I doubt that the wasp sandwich (who died from friponilic custard poisoning) will be to your taste.
