There are umpteen threads on the forum about Nosema, and various links to research...is this the one your thinking about.
http://scialert.net/qredirect.php?doi=pjbs.2005.1142.1145&linkid=pdf
Yep - That's the one thanks.
Did you look when you should give the thymol or Fumidil?
cumulative effect over years? - that is new to me and I have read everything about nosema.
But if you read other reseachers, nosema goes over during spring and vanishes. Nosema does not sprad any more in spring when bees fly and can make poo every day.
The paper states that treatment was given in spring and autumn
Cumulative effect is shown in fig 1 - Fumidil effect levels off after first year but thymol effect increases year on year.
Also the lab research paper mentioned in another post shows thymol to be effective in reducing nosema spores.
Interestingly R O B Manley says that he was never much troubled by nosema and he used thymol in his feed although this was for prevention of mould and I am not sure if he connected the effect of thymol on nosema.
Thymol is cheap, not toxic , stops mould in syrup, can be used for varroa treatment and seems to be effective in reducing nosema - I 'll certainly continue to use it.