Give the lady a coconut!
It's a serious case of chalkbrood, worse I've ever seen - the pepperbox pattern you can see is actually all the chalkbrood mummies which the bees have capped (hence the sunken appearance - but none appear greasy) and all the brood has long emerged. Harder to spot when the queen is laying well but I cheated here, I knew she was chalky after a Demarree last year where some frames were over 50% chalk, and was experimenting just to see how bad it would look after twelve months on fresh comb by conducting another Demarree whilst I was waiting for a new queen to see if the comb was salvageable (in actual fact, the bees have stayed with these frames and have cleared a lot of the chalkbrood out compared to last week) thus the reason there is no fresh brood there and no stores as it's all in the shallows underneath.
I had intended to bring my tweezers with me to open up a lot of the cells and take photographs of the mummies within - I forgot on both instances!
An interesting thing as well is I still took a nuc off this queen last year, when we (me and the SBI who was doing my DASH assesment) opened the nuc with the new queen we found loads of chalkbrood piled on the OMF, seems the bees had been clearing all the cells whilst waiting for the queen to mate. This year that queen's colony is now filling five supers and not a sign of any chalkiness. Not even early in the season.